Download e-book for kindle: A Symposium on Calcium and Cellular Function by A.W. Cuthbert

By A.W. Cuthbert

ISBN-10: 1349009059

ISBN-13: 9781349009053

ISBN-10: 1349009075

ISBN-13: 9781349009077

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Extra info for A Symposium on Calcium and Cellular Function

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In addition the linear relation between the area of the calcium transient and Pmax certainly does not prove that both the reaction of the myofibrils and aequorin with calcium ions is linear, although if both reactions are non-linear they must be non-linear in exactly the same way. When the duration of the stimulus pulse is increased beyond 300 msec there is a distinct change in the shape of the associated calcium transient response (Fig. 5a). The familiarS-shape rising phase is followed by a slow falling phase, and both phases are mediated by the membrane depolarization.

J. (1957). Biochim. biophys. Acta, 23, 80. , CHAPMAN, D. & DAWSON, R. M. C. (1969). Biochim. biophys. Acta, 183, 320. HAUSER, H. & DAwsoN, R. M. C. (1967a). Eur. J. , 1, 61 HAUSER, H. & DAWSON, R. M. C. (1967b). Biochem. , 105,401 HAUSER, H. & DAWSON, R. M. C. (1968). Biochem. , 109, 909 HAYDON, D. A. & TAYLOR, J. (1963). J. theoret. , 4, 281 HENDRICKSON, H. S, & FULLINGTON, J. G. (1965). Biochemistry, 4, 1599 HoDGKIN, A. L. & KEYNES, R. D. (1957). J. , 138, 253 HOFER, M. & KLEINZELLER, A. (1963).

At low calcium concentrations little binding occurs on zwitterionic phospholipids (for example, lecithin, phosphatidylethanolamine, sphingomyelin) in the physiological pH range, but some association takes place at higher concentrations. Monolayers of acidic phospholipids (for example, phosphatidylserine, phosphatidylinositol) avidly attract Ca2 +, provided the dissociations of the ionic groups on the polar head region produce a net negative charge. The adsorption isotherms are of the Langmuir type although deviations become apparent at high film pressures and Ca concentrations.

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A Symposium on Calcium and Cellular Function by A.W. Cuthbert

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